Ozempic, Wegovy, Mounjaro and other GLP-1 medications are hailed for weight loss—but they also interact with estrogen, cortisol, thyroid and more. If you’re navigating perimenopause, menopause or hormonal imbalance, understand the potential impacts on your cycle, mood and sleep. Read on for science-backed insights and tips on discussing GLP-1 drugs with your healthcare provider.